Diseases - Sheep

Annual Ryegrass Toxicity

Other Names

ARGT

Species

All.

Description

Annual ryegrass toxicity is a poisoning of livestock caused by ingestion of annual ryegrass (Lolium rigidum) that has been infected by a specific toxic bacterium. The bacteria are carried into the plant by a parasitic nematode and bacterial proliferation then creates the toxin. As plants mature and dry off (around hay making time), toxin levels may rise and peak.

ARGT occurs in the extensive WA and SA sheep-wheat belts where many export sheep are sourced. The feeding of contaminated hay may cause disease during the live export process.

Clinical Signs and Diagnosis

Signs include high stepping gait (hypermetria), staggering, collapse, trembling, terminal convulsions and death within one to two days. Affected animals may be found dead without observation of previous signs.

Signs appear from 4 days to several weeks after exposure and can persist intermittently for weeks after removal from the source. Mortality rates of 50% in animals with clinical signs are typical.

At necropsy there is variable congestion, oedema and haemorrhage of many organs, more obvious usually in lungs, kidneys, liver and brain.

In suspect pastures, a yellow slime may be observed on infected ryegrass heads.

Laboratory confirmation requires formalin-fixed liver and suspect grass or grass seed showing bacterial galls.

Differential diagnoses include enterotoxaemia and polioencephalomalacia. Other stagger syndromes such as phalaris, perennial ryegrass and paspalum staggers can look similar but don't have high numbers of acute deaths.

Treatment

No drug treatment is effective. Mildly affected sheep should be left undisturbed with access to water, feed and shade. Sheep in lateral recumbency should be euthanased.

Prevention

Deaths can be reduced by early recognition and removal from the source of the toxin.

Hay and seed heads can be tested using an ELISA to assess risks of using hay for feeding (contact your state animal health laboratory).

Syndromes