Shy feeders require special attention and management. The primary treatment is to separate affected animals to pens with fewer but similar age, size and sex animals, and feed roughage. From there, pellets can slowly be reintroduced to the ration and the number of animals in the pen eventually increased, if necessary, to relieve crowding elsewhere.
Additional treatments may be warranted depending on the results of examination of affected animals.
If ketosis is suspected, consider intravenous administration of dextrose and oral administration of propylene glycol. Transfer of rumen fluid from a healthy donor may be beneficial for animals where rumen microflora have been disrupted by inappetence, acidosis or oral antibiotics.
Antibiotics (procaine penicillin, erythromycin, or ceftiofur) and non-steroidal anti-inflammatory drugs (flunixin meglumine, ketoprofen, meloxicam, or tolfenamic acid) may be beneficial if infectious, septic, or painful disease is suspected or other efforts are ineffective. However, relapse at the end of a course of seemingly successful treatment may occur.
If apparent weight loss or reluctance to eat is becoming widespread, check the quality of water and feed, looking for any evidence of contamination or other changes that may affect intake.
A variety of injectable products are promoted as appetite stimulants (various combinations of vitamins often with other products), but efficacy is questionable. Glucocorticosteroids should be used with caution as they are immunosuppressive.
Although recommended in ketosis associated with lactation, they may be detrimental in other types of ketosis associated with pregnancy or over fatness.